First Wash The best way to completely clean off a plants leaves is to set it in the shower in the sink on outside and just rinse or hose it off. For regularly removing dust buildup from houseplants with large leaves such as a peace lily wipe the leaves gently with a cloth. How To Clean Houseplant Leaves And Why You Should House Plants House Plant Care Live House Plants Work from the base of each leaf to the tip. How to clean houseplant leaves . Rub a thin coat of mayonnaise over the leaves to keep them shiny. This will break through grease grime and caked on dirt faster. So for my small little spray bottle I did ½ cup of milk with ¾ cup water. Then go through with a rag and wipe them down. First mix up a ratio of milk to water. This is typically the best way to handle cleaning off larger plants with smaller leaves like trailing pothos plants. How to Clean Indoor Houseplants Shine the Leaves. Dont use any oil or any polish paint to enhance the shining of the leaves